Stem Cell Aging

Maria Carolina Florian

POSTDOCTORAL RESEARCHERS
  • Francesca Matteini
  • Rebecca Andersson
  • Surya Cayre
PREDOCTORAL RESEARCHERS
  • Alba Ferrer Perez
  • Barbara Walter
  • Eleni Nikolopoulou
SCIENTIFIC SUPPORT
  • Javier Lozano Bartolome
  • Sara Montserrat Vazquez
  • Eva María Mejía Ramírez De Arellano
  • Francesco Maria Affuso
Regenerative Medicine
Regenerative Medicine

Scientific production

5

PAPERS

Average IF: 14,910

2

LED PAPERS

Average IF: 14,208

3 PUBLICATIONS IN FIRST DECILE

3 PUBLICATIONS IN FIRST QUARTILE

3 PUBLICATIONS IN OPEN ACCESS

Selected publications

  • Montserrat Vazquez S, Ali NJ, Matteini F, Lozano J, Zhaowei T, Mejia Ramirez E, Marka G, Vollmer A, Soller K, Sacma M, Sakk V, Mularoni L, Mallm JP, Plass M, Zheng Y, Geiger H, Florian MC. Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice. npj Regen. Med. 2022;7(1):doi:10.1038/s41536-022-00275-y.
  • Andersson R, Florian MC. Living a longer life: unique lessons from the naked mole-rat blood system. EMBO J. 2022;doi:10.15252/embj.2022111759.
  • Matteini F, Florian MC. The gut-bone marrow axis a novel player in HSC aging Comment. Blood. 2022;139(1):3-4. doi:10.1182/blood.2021014134.
  • Bogeska R, Mikecin AM, Kaschutnig P, Fawaz M, Büchler Schäff M, Le D, Ganuza M, Vollmer A, Paffenholz SV, Asada N, Rodriguez Correa E, Frauhammer F, Buettner F, Ball M, Knoch J, Stäble S, Walter D, Petri A, Carreño Gonzalez MJ, Wagner V, Brors B, Haas S, Lipka DB, Essers M, Weru V, Holland Letz T, Mallm JP, Rippe K, Krämer S, Schlesner M, McKinney Freeman S, Florian MC, King KY, Frenette PS, Rieger MA, Milsom MD. Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging. Cell Stem Cell. 2022;doi:10.1016/j.stem.2022.06.012.
  • Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, Ermolaeva M, Ewald CY, Ferrucci L, Florian MC, Fortney K, Freund A, Georgievskaya A, Gladyshev VN, Glass D, Golato T, Gorbunova V, Hoejimakers J, Houtkooper RH, Jager S, Jaksch F, Janssens G, Jensen MB, Kaeberlein M, Karsenty G, de Keizer P, Kennedy B, Kirkland JL, Kjaer M, Kroemer G, Lee KF, Lemaitre JM, Liaskos D, Longo VD, Lu YX, MacArthur MR, Maier AB, Manakanatas C, Mitchell SJ, Moskalev A, Niedernhofer L, Ozerov I, Partridge L, Passegué E, Petr MA, Peyer J, Radenkovic D, Rando TA, Rattan S, Riedel CG, Rudolph L, Ai R, Serrano M, Schumacher B, Sinclair DA, Smith R, Suh Y, Taub P, Trapp A, Trendelenburg AU, Valenzano DR, Verburgh K, Verdin E, Vijg J, Westendorp RGJ, Zonari A, Bakula D, Zhavoronkov A, Scheibye Knudsen M. Meeting Report: Aging Research and Drug Discovery. Aging (Albany NY). 2022;14(undefined):530-543. doi:10.18632/aging.203859.

Research highlights

PROJECTS

2 Granted competitive projects
6 Ongoing competitive projects

NETWORKS

AGAUR SGR GRC

Selected projects

  • 21CEE002. ReSinAge: Regeneration of Sinusoidal niches to preserve hematopoiesis after chemotherapy on Ageing. COMISSIÓ EUROPEA. Budget: 1997360. 2021-2026. PI: Florian, Maria Carolina.
  • 20PSJ026. Deep Learning to Dissect the Interaction between Leukemic Cells and the Ageing Niche. FUNDACIÓ “LA CAIXA”. Budget: 652045,7967. 2020-2023. PI: Florian, Maria Carolina.
  • ERA21005. PIXEL -TRANSCAN-3 2022 — FLORIAN, CAROLINA. AEC / ISCIII. Budget: 242529. 2022-9999. PI: Florian, Maria Carolina.
  • 20MEC008. Ayudas Ramón y Cajal. Ministerio de Ciencia e Innovación. Budget: 208600. 2020-2023. PI: Florian, Maria Carolina.
  • MCI21047. Rejuvenating superhenancers in aged hematopoietic stem cells by tareting Cdk8. Ministerio de Ciencia e Innovación. Budget: 193600. 2022-2025. PI: Florian, Maria Carolina.