Sarcoma

Oscar Martinez-Tirado

PRINCIPAL INVESTIGATORS
  • Xavier Garcia del Muro Solans
CLINICAL RESEARCHERS
  • Francesc Xavier Sanjuan Garriga
  • Juan Jesus Martin Liberal
POSTDOCTORAL RESEARCHERS
  • Mariona Chicón Bosch
  • Laura Santana Viera
PREDOCTORAL RESEARCHERS
  • Paola Monaco
  • Sara Sanchez Serra
SCIENTIFIC SUPPORT
  • Roser Lopez Alemany
  • Susana Maqueda Marcos
  • Manuel Gris Lorente
Cancer
Oncobell

Scientific production

13

PAPERS

Average IF: 14,233

1

LED PAPER

Average IF: 3,121

5 PUBLICATIONS IN FIRST DECILE

11 PUBLICATIONS IN FIRST QUARTILE

10 PUBLICATIONS IN OPEN ACCESS

Selected publications

  • Casali PG, Blay JY, Abecassis N, Bajpai J, Bauer S, Biagini R, Bielack S, Bonvalot S, Boukovinas I, Bovee JVMG, Boye K, Brodowicz T, Buonadonna A, De Alava E, Dei Tos AP, del Muro XG, Dufresne A, Eriksson M, Fedenko A, Ferraresi V, Ferrari A, Frezza AM, Gasperoni S, Gelderblom H, Gouin F, Grignani G, Haas R, Hassan AB, Hindi N, Hohenberger P, Joensuu H, Jones RL, Jungels C, Jutte P, Kasper B, Kawai A, Kopeckova K, Krakorova DA, Le Cesne A, Le Grange F, Legius E, Leithner A, Lopez Pousa A, Martin Broto J, Merimsky O, Messiou C, Miah AB, Mir O, Montemurro M, Morosi C, Palmerini E, Pantaleo MA, Piana R, Piperno Neumann S, Reichardt P, Rutkowski P, Safwat AA, Sangalli C, Sbaraglia M, Scheipl S, Schoffski P, Sleijfer S, Strauss D, Strauss SJ, Hall KS, Trama A, Unk M, van de Sande M, van der Graaf W, van Houdt WJ, Frebourg T, Gronchi A, Stacchiotti S, ESMO Guidelines C, E, G. Gastrointestinal stromal tumours: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 2022;33(1):20-33. doi:10.1016/j.annonc.2021.09.005.
  • Gounder MM, Razak AA, Somaiah N, Chawla S, Martin Broto J, Grignani G, Schuetze SM, Vincenzi B, Wagner AJ, Chmielowski B, Jones RL, Riedel RF, Stacchiotti S, Loggers ET, Ganjoo KN, Le Cesne A, Italiano A, Garcia Del Muro X, Burgess M, Piperno Neumann S, Ryan C, Mulcahy MF, Forscher C, Penel N, Okuno S, Elias A, Hartner L, Philip T, Alcindor T, Kasper B, Reichardt P, Lapeire L, Blay JY, Chevreau C, Valverde Morales CM, Schwartz GK, Chen JL, Deshpande H, Davis EJ, Nicholas G, Gröschel S, Hatcher H, Duffaud F, Herráez AC, Beveridge RD, Badalamenti G, Eriksson M, Meyer C, von Mehren M, Van Tine BA, Götze K, Mazzeo F, Yakobson A, Zick A, Lee A, Gonzalez AE, Napolitano A, Dickson MA, Michel D, Meng C, Li L, Liu J, Ben Shahar O, Van Domelen DR, Walker CJ, Chang H, Landesman Y, Shah JJ, Shacham S, Kauffman MG, Attia S. Selinexor in Advanced, Metastatic Dedifferentiated Liposarcoma: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial. J. Clin. Oncol. 2022;40(22):2479-2490. doi:10.1200/JCO.21.01829.
  • Archilla Ortega A, Domuro C, Martin Liberal J, Muñoz P. Blockade of novel immune checkpoints and new therapeutic combinations to boost antitumor immunity. J. Exp. Clin. Cancer Res. 2022;41(1):62-62. doi:10.1186/s13046-022-02264-x.
  • Pascual Pasto G, Castillo Ecija H, Unceta N, Aschero R, Resa Pares C, Gómez Caballero A, Vila Ubach M, Muñoz Aznar O, Suñol M, Burgueño V, Gomez Gonzalez S, Sosnik A, Ibarra M, Schaiquevich P, de Álava E, Tirado OM, Mora J, Carcaboso AM. SPARC-mediated long-term retention of nab-paclitaxel in pediatric sarcomas. J Control Release. 2022;34281-92. doi:10.1016/j.jconrel.2021.12.035.
  • García Domínguez DJ, Hajji N, López Alemany R, Sánchez Molina S, Figuerola Bou E, Morón Civanto FJ, Rello Varona S, Andrés León E, Benito A, Keun HC, Mora J, Tirado ÓM, de Álava E, Hontecillas Prieto L. Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1. Oncogene. 2022;41(18):2638-2650. doi:10.1038/s41388-022-02279-w.

Research highlights

PROJECTS

4 Granted competitive projects
12 Ongoing competitive projects

14 Started clinical trials
101 Ongoing clinical trials

PUBLISHED WORKS

1 Clinical guideline
1 Thesis

INNOVATION

1 Patent
1 License
1 Spin off

NETWORKS

AGAUR SGR GRC

Selected projects

  • FIS21126. TILS TREATMENT IN ADVANCED TUMORS WITH ALTERATIONS IN THE SWI/SNF COMPLEX: THE TILTS STUDY. Instituto de Salud Carlos III (ISCIII). Budget: 1081914,72. 2022-2025. PI: Martín Liberal, Juan.
  • 20MAR001. Molecular analysis of the metastatic process in developmental tumors. Fundació TV3. Budget: 300000. 2020-2023. PI: MARTINEZ TIRADO, OSCAR.
  • 19ACL231. ESTUDIO DE FASE 1B/2 DE LY3200882 Y PEMBROLIZUMAB EN PACIENTES CON CÁNCER AVANZADO. Budget: 267326,4. 2019- . PI: Martín Liberal, Juan.
  • 2021-070-1. PROSPECTIVE COLLECTION OF DONOR TISSUE AND WHOLE BLOOD OR LEUKAPHERESIS PRODUCT FROM PATIENTS WITH SOLID TUMOURS TO ENABLE DEVELOPMENT OF METHODS FOR THE MANUFACTURING OF CLONAL NEOANTIGEN T CELL PRODUCTS (cNeT). ACHILLES THERAPEUTICS UK LIMITED. Budget: 220881,12. 2021- . PI: Martín Liberal, Juan.
  • 20ACL101. A PHASE 2 STUDY OF REGN2810, A FULLY HUMAN MONOCLONAL ANTIBODY TO PROGRAMMED DEATH – 1 (PD-1), IN PATIENTS WITH ADVANCED CUTANEOUS SQUAMOUS CELL CARCINOMA. REGENERON PHARMACEUTICAL, INC. Budget: 203366,88. 2020- . PI: Martín Liberal, Juan.